Transcriptional Signatures Sensitive to Cognition-Improving Pharmacological Treatments in Fragile X Syndrome

June 27, 2022

This team is defining Fragile X “molecular signatures” to use as biomarkers. They’ll test CBD and other drugs in mice and compare findings to human brain data.

Read More »

Built Jobsite BBQ Raising Funds for Fragile X Research

May 5, 2022

Built employee Jason and his team hosted a BBQ fundraiser for FRAXA after his sons, Jaxson and Alex, were diagnosed with Fragile X.

Read More »

Repurposing FDA-Approved Drugs to Treat Major Depressive Disorder in Fragile X Syndrome

April 24, 2022

Depression is common in Fragile X, but current antidepressants need FMRP to work. Researchers will screen FDA-approved drugs to find effective options for FXS.

Read More »

FMR1 Renamed to Fragile X Messenger Ribonucleoprotein 1

April 13, 2022

The FMR1 gene is renamed to “Fragile X Messenger Ribonucleoprotein 1” gene. The Fragile X protein, FMRP, is "Fragile X Messenger Ribonucleoprotein." "Mental retardation" is not used.

Read More »

VLM Commodities Charity Week Raises $10,000 for Fragile X Research

April 8, 2022

“Living with Fragile X is what we do—we keep going forward,” Lou shared. “FRAXA gives purpose, and I’m proud to support Charity Week.”

Read More »

How FRAXA Prioritizes Research, Explained

April 7, 2022

Dr. Mike Tranfaglia explains how FRAXA prioritizes research. "It’s not either-or. It’s not we have a definitive treatment or we have a new drug treatment or we have a repurposing treatment.

Read More »

Aggression, Other Fragile X Behaviors Tend to Ease Over Teenage Years

April 5, 2022

Behavioral problems such as hyperactivity and aggression are more frequent in children with Fragile X syndrome, becoming less common as they grow through adolescence into adulthood.

Read More »

Cape Coral Touch-A-Truck, Free, Family-Friendly Event

March 31, 2022

Join EHL Fragile X Foundation’s free Touch-A-Truck in Cape Coral! Explore fire trucks, police bikes, ambulances, swamp buggies, and more.

Read More »

Wine and Friends Are a Great Blend for Fragile X Research

March 25, 2022

Debra and Kevin hosted their first annual event for FRAXA in honor of their grandson Jackson, who has Fragile X syndrome.

Read More »

What FRAXA Is Excited about in the Upcoming Fragile X Research Grants, Explained

March 24, 2022

Many new clinical trials are starting, with existing and investigational drugs and other treatment strategies that have been tested in the Fragile X mouse models moving to patients in clinical trials.

Read More »

Gordon Research Conference for Fragile X and Autism-Related Disorders, Explained

March 17, 2022

The Fragile X and Autism-Related Disorders Gordon Research Conference is a biannual event, an international forum for the presentation and discussion of frontier research in these conditions.

Read More »

Making Mittens for Fragile X

February 25, 2022

Carol spends over 2 hours crafting each fleece-lined mitten. Her handmade creations warm hands and support Fragile X research.

Read More »

Meet Archie!

February 18, 2022

Archie really loves fire engines and trains as well as bells. Archie has had a few struggles this past year as his mom was diagnosed with cancer but thankfully she’s now cancer free.

Read More »
Banerjee team at College of Staten Island

Correcting Fragile X Syndrome Deficits by Targeting Neonatal PKCε Signaling in the Brain

February 17, 2022

Enhancing PKCε in early development normalized oxytocin, AMPAR signaling, and adult behavior in Fragile X mice, highlighting PKCε as a promising therapeutic target.

Read More »

Climbing 3 Mountains for Fragile X Research

February 4, 2022

Michael Leonard climbed three mountains in 24 hours to honor his son, Cole, who lives with Fragile X syndrome. A father’s love knows no limits.

Read More »

Potential Upcoming Advances in Fragile X Research

February 3, 2022

Dr. Peter Kind and Dr. Nahum Sonenberg share their optimism about the next 10 years of Fragile X research. They discuss where they think the next big discoveries will emerge.

Read More »
LEPAGE_jean-francois_CORBIN_francois

Lovamix: Clinical Trial of Combined Treatment of Minocycline and Lovastatin in Fragile X Syndrome

February 3, 2022

FRAXA funded the LovaMiX trial of lovastatin + minocycline for Fragile X. 2022 results show safety and support continued study of this dual-target treatment approach.

Read More »

FRAXA’s Most Successful End-Of-Year Campaign Ever!

January 11, 2022

Together, we made history! FRAXA’s 2021 campaign was our most successful ever, fueling hope for treatments and a cure for Fragile X.

Read More »

Neurodevelopmental Drug Development Summit Presentation

January 7, 2022

FRAXA president and co-founder, Katie Clapp, and and FRAXA Scientific Advisor, Dr. Elizabeth Berry-Kravis, presented at the Neurodevelopmental Drug Development Summit.

Read More »

Reactivating the Fragile X Gene in Young Mice Reverses Symptoms

December 28, 2021

Fragile X syndrome might be treated by reactivating the gene which is shut down in the syndrome. Researchers were able to reduce FXS symptoms by inserting the FMR1 gene into the brains of young mice.

Read More »

Meet Jonathan!

December 26, 2021

Jonathan has changed a lot as he’s gotten older. He’s become calmer and less aggressive and has developed into a very social man! He still struggles with anxiety.

Read More »

10 Year Vision for Collaborations That Transform Fragile X and Autism Research

December 20, 2021

FRAXA’s Dr. Mike Tranfaglia talks with Autism Science Foundation’s Allison Singer about collaborations between the Fragile X community and other disability organizations as we look to the next 10 years.

Read More »
PALS Committee

Patrick’s PALS Still Shines Strong Even in the Face of COVID

December 13, 2021

Patrick’s PALS 25th Annual Fundraiser raised $140K for FRAXA in 2021, proof that the spirit and generosity behind this event never fade.

Read More »

16th Annual Fragile X Poker Run Raises nearly $29,000

December 3, 2021

The 16th Annual Fragile X Poker Run brought friends from 10 states and Israel together, raising $29K for FRAXA research!

Read More »

Categories

FRAXA Funded Research

Current Research Grants (37)