Finding effective treatments and, ultimately, a cure for fragile X syndrome, the most common inherited cause of autism.

Latest Fragile X News & Updates

Can CRISPR Cure Fragile X Syndrome?

CRISPR/Cas9 was used by MIT researchers to remove the molecular tags that keep the mutant gene shut off in fragile X syndrome neurons and resulted in some of them producing protein normally. Much work is being done right now, with exciting new discoveries coming at a fast and furious pace.
Read More

Newly Diagnosed with Fragile X – What Comes Next?

Jessica Haugen and Jeff Eliason received the phone call every parent dreads in October 2012. Their son’s pediatrician told them their son, Larry, then 1, had fragile X syndrome (FXS) and “there’s nothing you can do about it.” The couple reacted similarly to how other newly diagnosed parents receiving these results. Denial. Discouragement. Depression.
Read More

NIH Request for Feedback on Fragile X Research Plan

The NIH is updating a Research Plan for fragile X syndrome and the associated disorders of FXTAS (fragile X-associated tremor/ataxia syndrome) and FXPOI (fragile X-associated primary ovarian insufficiency) that was originally created in 2009 by experts convened by the them. FRAXA team members were part of these working groups, giving guidance on priority areas and most promising research directions and will be once again. The NIH is requesting input from families and other members of the fragile X community.
Read More

Fragile X Conference at Boston Children’s Hospital

FRAXA and the Pierce Foundation are partners with Boston Children's Hospital's Fragile X Program and are pleased to help bring this important fragile X conference to the greater Boston community. Two FRAXA-supported researchers, Dr. Craig Erickson from Cincinnati Children's Hospital and Dr. Carol Wilkinson from Boston Children's Hospital will present their current work.
Read More

What is Fragile X?

Fragile X syndrome is the most common inherited cause of autism and intellectual disabilities. It affects 1 in 4000 boys and 1 in 6000 girls of all races worldwide.
Fragile X occurs when a single gene shuts down. Our children lack one protein vital for normal brain function.

Learn More
Jasper, photo contest winner

Finding a Cure

FRAXA is committed to finding effective treatments and ultimately a cure for fragile X syndrome. FRAXA has funded over $26,000,000 in research worldwide; hundreds of teams are in their labs right now, testing, seeking, discovering.

Learn More

Be a Friend of FRAXA

Friends of FRAXA are parents, grandparents, researchers, sisters, brothers, teachers. Meet our families – hear their stories. We welcome you as a Friend of FRAXA.

Sign Up for e-News

Treatment approaches are in the pipeline and clinical trials are underway. Join our community and keep up with the latest exciting advances.

Sign Up

You Can Help!

FRAXA is run by parents; we are motivated by our children and others like them. Our management/general expenses are under 4% so when you donate to FRAXA, your dollars count!

Donate Now