Finding effective treatments and, ultimately, a cure for fragile X syndrome, the most common inherited cause of autism.

Latest Fragile X News & Updates

FRAXA Funded Researchers Present at MA Fragile X Conference

On Saturday Boston Children’s Hospital (BCH) hosted a fragile X educational conference, Success Strategies for Individuals and Families Impacted by Fragile X and two of our funded researchers, Dr. Craig Erickson, and Carol Wilkinson, MD, PhD, presented giving an update on their current fragile X clinical trials. Both being funded by FRAXA.
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Fragile X Clinical Trial of New PDE4 Inhibitor from Tetra funded by FRAXA

With a $200,043 grant from FRAXA Research Foundation in April 2018, Dr. Elizabeth Berry-Kravis will conduct a Phase 2 clinical trial of a new PDE4 inhibitor from Tetra Discovery Partners in adults with fragile X syndrome.
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Takeaways from Fragile X Advocacy Day

In the first week of March I attended my first Fragile X Advocacy Day to meet with many of the Massachusetts delegation to Congress. While this was my first time advocating for fragile X research, I’ve been a longtime lung cancer research advocate and have met with many of the same representatives in the past. It was a pleasure to meet with many of the families as my participation in Advocacy Day was in the spirit of “we are all in this together”.
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Reintroducing FMRP to Reduce Symptoms of Fragile X Syndrome

FRAXA Research Foundation and the Fragile X Research Foundation of Canada have awarded a grant of $100,000 over two years to Dr. Raymond Turner at the University of Calgary in Alberta, Canada. Dr. Turner and postdoctoral fellow Xiaoqin Zhan, PhD are attempting to reactivate a segment of FMRP to reverse symptoms of fragile X in a mouse model of the disease to reduce abnormal behaviors.
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What is Fragile X?

Fragile X syndrome is the most common inherited cause of autism and intellectual disabilities. It affects 1 in 4000 boys and 1 in 6000 girls of all races worldwide.

Fragile X occurs when a single gene shuts down. Our children lack one protein vital for normal brain function.

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Finding a Cure

FRAXA is committed to finding effective treatments and ultimately a cure for fragile X syndrome. FRAXA has funded over $26,000,000 in research worldwide; hundreds of teams are in their labs right now, testing, seeking, discovering.

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Friends of FRAXA are parents, grandparents, researchers, sisters, brothers, teachers. Meet our families – hear their stories. We welcome you as a Friend of FRAXA.

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Treatment approaches are in the pipeline and clinical trials are underway. Join our community and keep up with the latest exciting advances.

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You Can Help!

FRAXA is run by parents; we are motivated by our children and others like them. Our management/general expenses are under 4% so when you donate to FRAXA, your dollars count!

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Explore Current Fragile X Research

FRAXA-funded researchers around the world are leading the way towards effective treatments and ultimately a cure.