Finding effective treatments and, ultimately,


Our Impact to Date


Direct Investment in Fragile X Research

What is Fragile X Syndrome?

Fragile X syndrome (FXS) is the most common inherited cause of autism and intellectual disabilities. It affects 1 in 4,000 boys and 1 in 6,000 girls worldwide.

Fragile X syndrome occurs when a single gene on the X chromosome shuts down. This gene makes a protein needed for normal brain development. In FXS it does not work properly, the protein is not made, and the brain does not develop as it should.

Learn more about fragile X syndrome

How Does FRAXA Help?

FRAXA’s mission is to find effective treatments and ultimately a cure for fragile X syndrome. We directly fund research grants and fellowships at top universities around the world. We partner with biomedical and pharmaceutical companies, large and small, to bridge the gap between research discoveries and actual treatments.

Treatments for fragile X are likely to help people affected by autism, Alzheimer’s, and other brain disorders.

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Upcoming Events

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Latest Fragile X News & Updates

FRAXA Biotech Games™ – Broadening the Base for Fragile X Research

We are proud to announce that the First Annual FRAXA Biotech Games™ are coming to Boston in September 2018. This event is a “friendly” competition between leading biotech companies in greater Boston in a series of back yard lawn games including Cornhole, KanJam, Bucketball and Ladder golf. The event will take place on the campus of Massachusetts Institute of Technology (MIT) and funds raised will support a FRAXA fragile X research grant to the lab of Dr. Mark Bear at the MIT Picower Institute.
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Three-Dimensional Model for Identifying Fragile X Treatments

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Pharmacological Tolerance in the Treatment of Fragile X Syndrome

With a $90,000 grant from FRAXA Research Foundation, Dr. Patrick McCamphill and Dr. Mark Bear at Massachusetts Institute of Technology (MIT) will further investigate drug tolerance and ways to overcome it. 
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Current Fragile X Research

Funded by FRAXA Research Foundation


Teams actively researching fragile X

Current Research Grants
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Pharmaceutical and Biomedical Partners

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ongoing fragile x clinical trials and studies

Current Clinical Trials & Studies
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Countries are home to research teams

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gene therapy and protein replacement studies

Current Studies
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