Finding effective treatments and, ultimately,


Our Impact to Date


Direct Investment in Fragile X Research

What is Fragile X Syndrome?

Fragile X syndrome (FXS) is the most common inherited cause of autism and intellectual disabilities. It affects 1 in 4,000 boys and 1 in 6,000 girls worldwide.

Fragile X syndrome occurs when a single gene on the X chromosome shuts down. This gene makes a protein needed for normal brain development. In FXS it does not work properly, the protein is not made, and the brain does not develop as it should.

Learn more about fragile X syndrome

How Does FRAXA Help?

FRAXA’s mission is to find effective treatments and, ultimately, a cure for fragile X syndrome. We directly fund research grants and fellowships at top universities around the world. We partner with biomedical and pharmaceutical companies, large and small, to bridge the gap between research discoveries and actual treatments.

Treatments for fragile X are likely to help people affected by autism, Alzheimer’s, and other brain disorders.

Donate to FRAXA's mission

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Latest Fragile X News & Updates

Study Examines Behavioral Traits of Fragile X Patients Without Autism

Patients with fragile X syndrome who don’t meet the cut-off for a diagnosis of autism show a decrease in impulsivity and repetitive questioning over time, when compared with patients who do, a new study shows.
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Understanding and Reversing Hypersensitivity to Sounds in Fragile X Syndrome

With a $90,000 grant from FRAXA Research Foundation over 2018-2019, Drs. Devin Binder, Iryna Ethell, and Patricia Pirbhoy at the University of California at Riverside aim to understand - and reverse - hypersensitivity to sound in fragile X syndrome.
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22nd Patrick’s PALS Basketball Tournament Raises $125,000 for Fragile X Research!

The Patrick’s PALS 22nd Annual 3-on-3 Basketball Tournament benefiting FRAXA Research Foundation took place on Saturday, June 2, 2018, at the Buckingham Browne & Nichols School (BB&N) in Cambridge. 36 teams signed up and were squeezed into the 32-team, double-elimination format raising another $125,000 for fragile X research!
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Current Fragile X Research

Funded by FRAXA Research Foundation


Teams actively researching fragile X

Current Research Grants
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Pharmaceutical and Biomedical Partners

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ongoing fragile x clinical trials and studies

Current Clinical Trials & Studies
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Countries are home to research teams

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gene therapy and protein replacement studies

Current Studies
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