Ketogenic Diet Eases Symptoms in Fragile X Male Mice
Westmark Lab is studying sleep patterns in Fragile X mice, working with UW-Madison to develop tools that speed EEG data analysis
Meet Jackson!
Meet #FriendofFRAXA Jackson! If you would like to nominate someone as a #FriendofFRAXA, we welcome all who have been touched by Fragile X, including friends, grandparents, siblings, professionals and companions alike to become a #FriendofFRAXA with the goal of putting a face to Fragile X for those who may not know someone directly.
Drug Repurposing for Rare Disease and the Future of Health – The Genetics Podcast
In this episode Dr. Patrick Short talks to Dr. Bruce Bloom, CCO of Healx, and Dr. Mike Tranfaglia, CSO of FRAXA. about drug repurposing, machine learning, and Fragile X syndrome.
Considering Available Drugs for Fragile X: My Favorite Combination (So Far)
Which of the available drugs are best for managing fragile X syndrome? Most drugs have “off-target” effects which can have key advantages in some cases.
Less Active Immune System Evident in Fragile X Patients, Study Suggests
People with Fragile X syndrome are more likely to develop infections but less susceptible to autoimmune disorders than the overall population, a study found.
Results Reported: Using EEG Responses to Sound for Fragile X Drug Discovery
An obstacle in FXS research has been lack of reliable, unbiased biomarkers to assess herapies. This team found striking similarity in EEG biomarkers between mice and humans.
A Tribute to Mary Higgins Clark
Mary Higgins Clark, beloved author and Fragile X advocate, passed at 92. Her $1M gift in 1997 helped put FRAXA on the map for research.
Should You Participate in a Fragile X Clinical Trial?
A Fragile X clinical trial of a new PDE4D allosteric inhibitor from Tetra Therapeutics is nearly complete. The drug has a unique mechanism of action that might improve cognitive and memory function.
Meet Will!
Meet #FriendofFRAXA Will! If you would like to nominate someone as a #FriendofFRAXA, we welcome all who have been touched by Fragile X, including friends, grandparents, siblings, professionals and companions alike to become a #FriendofFRAXA with the goal of putting a face to Fragile X for those who may not know someone directly.
Thankful is an Understatement
Thanks to our incredible supporters, FRAXA met its $750K goal before 2020—proof that together, we can overcome any challenge!
31 Nights of Light with FRAXA Research Foundation
The Boston Prudential Center featured FRAXA in its 31 Nights of Light, shining bright for Fragile X awareness this December!
Boston Bruins Fans and Volunteers raise $18,500 for Fragile X Research
The Bruins Foundation selected FRAXA again for their 50/50 raffle, raising $37K during the Nov 23 game against the Minnesota Wild!
Meet Caleb!
Meet #FriendofFRAXA Caleb! If you would like to nominate someone as a #FriendofFRAXA, we welcome all who have been touched by Fragile X, including friends, grandparents, siblings, professionals and companions alike to become a #FriendofFRAXA with the goal of putting a face to Fragile X for those who may not know someone directly.
Jim Cantore Assists on an Absolutely Successful #GivingTuesday
With Jim Cantore’s help and 130+ donors, FRAXA raised $95,500 on #GivingTuesday—funding two year-long Fragile X research grants!
New Partners Aim to Accelerate the Discovery and Repurposing of Medicines for Rare Neurological Diseases
Healx has launch a global Rare Treatment Accelerator program to tackle Fragile X syndrome and 39 other rare diseases. It all started with a small FRAXA grant to repurpose available drugs for Fragile X.
Meet Jed & Kit!
Meet #FriendofFRAXA Jed & Kit! If you would like to nominate someone as a #FriendofFRAXA, we welcome all who have been touched by Fragile X, including friends, grandparents, siblings, professionals and companions alike to become a #FriendofFRAXA with the goal of putting a face to Fragile X for those who may not know someone directly.
Genes & Gems Raises $56,000 for Fragile X Research!
Ohio families hosted the unforgettable Genes & Gems event on Nov 16, 2019 at the Renaissance Columbus Hotel to support FRAXA research.
Meet Jack!
Meet #FriendofFRAXA Jack! If you would like to nominate someone as a #FriendofFRAXA, we welcome all who have been touched by Fragile X, including friends, grandparents, siblings, professionals and companions alike to become a #FriendofFRAXA with the goal of putting a face to Fragile X for those who may not know someone directly.
National Institutes of Health Releases Fragile X Strategic Plan
FRAXA’s Elle Skala and supporter Mary Beth Busby visited NIH as the new Strategic Plan for Fragile X was released, shaping federal research priorities for years.
Meet Anthony!
Meet #FriendofFRAXA Anthony! If you would like to nominate someone as a #FriendofFRAXA, we welcome all who have been touched by Fragile X, including friends, grandparents, siblings, professionals and companions alike to become a #FriendofFRAXA with the goal of putting a face to Fragile X for those who may not know someone directly.
Potassium Channel Modulators to Treat Fragile X
FRAXA-backed Yale discoveries tied Fragile X to Kv3.1/Slack channel defects—leading to a partnership with Autifony to develop targeted treatments.
Meet Jagger!
Meet #FriendofFRAXA Jagger! If you would like to nominate someone as a #FriendofFRAXA, we welcome all who have been touched by Fragile X, including friends, grandparents, siblings, professionals and companions alike to become a #FriendofFRAXA with the goal of putting a face to Fragile X for those who may not know someone directly.
A Personal Touch to Supporting Fragile X Research
As the holidays near, take a moment to make a difference. Your year-end gift to FRAXA helps change the future for Fragile X families.
Targeting Adiponectin to Treat Fragile X Syndrome
Boosting adiponectin, a hormone that regulates metabolism, may improve cognition and behavior in Fragile X. Early results suggest it can restore brain plasticity.