FRAXA’s mission is to find effective treatments and a cure for Fragile X by directly funding the most promising research. FRAXA’s research portfolio spans the spectrum of basic science, pre-clinical, and clinical research — all coordinated to make the most of each dollar. We maintain a diversified approach, developing several treatment strategies in parallel, since success is never certain in developing a single drug. We continue to fund research to define the precise defect in the Fragile X brain, because these basic studies may yield additional important therapeutic targets.

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We fund approximately $1.5 million in postdoctoral fellowships and investigator-initiated program grants each year, with an application deadline of February first. This section provides materials including:


Research Meetings

FRAXA Investigators Meeting

FRAXA organizes and sponsors conferences where scientists share discoveries, plan collaborations, and bring new researchers into the field.

  • FRAXA Investigators Meetings run every 2 years (2013, 2015, etc.)
  • Gordon Conferences on Fragile X and Autism run alternate years (2014, etc.)


Research Resources

Resources available to researchers include a large array of FMR1 mutant mouse models. Details in this section.


  • mutant mouse resource
  • reagents, experimental compounds
  • antibodies
  • tissue

Related Links

>Summary of Findings: What do we know and how close are we to a cure?

>Treatment Trials: Here you will find a listing of trials and studies currently accepting participants with Fragile X.

>Research Reports: Review all FRAXA grants here. Each FRAXA investigator has a page about his/her work