Fragile X Research Funding of $1 Million Offered for 2021

Fragile X Research Funding of $1 Million Offered for 2021

FRAXA plans to fund $1 million for a generous number of Fragile X research grants and fellowships in 2021. Our mission is to find specific treatments and ultimately a cure for Fragile X syndrome. We aim to bring practical treatment into current medical practice as quickly as possible; we prioritize projects that have a clear practical application and the results of which will be shared in a timely fashion.

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Integrating Human and Mouse Studies in Fragile X Syndrome – an NIH Center Approach

Integrating Human and Mouse Studies in Fragile X Syndrome – an NIH Center Approach
FRAXA Seminar Series This virtual seminar series addresses a wide range of current topics in Fragile X research. Hosted by FRAXA and organized by Michael Tranfaglia, MD and Patricia Cogram, PhD, sessions feature outstanding speakers from universities and the biotech and pharmaceutical industries.  Presentation Summary Craig Erickson - Translational medicine and mechanistic studies of brain neurophysiology in Fragile X Syndrome: A NIH Center Overview Ernest Pedapati - Network Mechanisms, Biomarkers, and Pharmacology of Fragile X Syndrome in Humans Devin Binder - Network Mechanisms of Neurophysiology and Behavior in mouse models of Fragile X Syndrome Kimberly Huber - FMRP Regulation of local and long-range neocortical circuits in the mouse: Links with EEG phenotypes About the SpeakersCraig A. Erickson, MD Professor of Psychiatry at Cincinnati Children's Hospital and the University of Cincinnati College of Medicine Craig Erickson is the director of the Cincinnati Fragile X Research and Treatment Center. Craig has devoted his careerRead more

Towards Understanding the Role of FMRP in Human Brain Development Using Brain Organoids

Towards Understanding the Role of FMRP in Human Brain Development Using Brain Organoids

Dr. Zhexing Wen and Dr. Peng Jin of the newly funded Fragile X Center of Excellence at Emory University School of Medicine join us in this seminar to present about Understanding the Role of FMRP in Human Brain Development Using Brain Organoids.

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Recruiting: Facematch Fragile X Project at University of Newcastle

Recruiting: Facematch Fragile X Project at University of Newcastle

The FaceMatch project is using computer face-matching technology to help find a diagnosis for children with intellectual disability (ID) where genetic testing has not provided an answer. As we know, the time prior to diagnosis is one of the toughest periods in the journey of our children and we hope that the inclusion of families such as yours with a known diagnosis may help those families who are still searching for a diagnosis.

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Department of Defense Medical Research Funding Guided by FRAXA Consumer Reviewers

Department of Defense Medical Research Funding Guided by FRAXA Consumer Reviewers

FRAXA nominated three individuals to join in the program this year. Over the past several weeks, Katie Clapp, Ellen Skala, and Jennifer Frobish participated in the evaluation of research applications submitted to the PRMRP. As consumer reviewers, they were full voting members (along with prominent scientists) at meetings to help determine how the $360 million appropriated by Congress for Fiscal Year 2020 will be spent on PRMRP research.

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Positive Results Reported in Phase II Fragile X Clinical Trial of PDE4D Inhibitor from Tetra Therapeutics

Positive Results Reported in Phase II Fragile X Clinical Trial of PDE4D Inhibitor from Tetra Therapeutics

Today, Tetra Therapeutics announces the first unequivocally positive phase 2 clinical trial in Fragile X syndrome, press release below. The results do not depend on carving out a subset of patients or post hoc analysis.

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University of Kansas BRAIN Lab Seeking Postdoctoral Fellow

University of Kansas BRAIN Lab Seeking Postdoctoral Fellow

The Life Span Institute at the University of Kansas currently is seeking one postdoctoral fellow interested in advancing their research skills and progressing towards a career as an independent, externally funded investigator studying autism spectrum (ASD) or related neurodevelopmental disorders (e.g., Fragile X syndrome, Down syndrome).

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Auditory System Dysfunction and Drug Tolerance in the Fragile X Mouse

Auditory System Dysfunction and Drug Tolerance in the Fragile X Mouse

FRAXA Research Foundation has awarded $90,000 over 2019-2021 to principal investigator Dr. Jay Gibson and postdoctoral fellow Dr. Andrew Holley at the University of Texas Southwestern Medical Center. They are investigating circuit mechanisms for auditory system dysfunction and drug tolerance in the Fragile X mouse model.

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Mechanisms and Biomarkers of Sensory Hypersensitivity in the fmr1 Knockout Mouse

Mechanisms and Biomarkers of Sensory Hypersensitivity in the fmr1 Knockout Mouse

In this Fragile X research webinar we hear from Devin K. Binder, MD, PhD, Professor, University of California at Riverside Medical School and Khaleel Razak, PhD, Professor, University of California at Riverside as they present about Mechanisms and Biomarkers of Sensory Hypersensitivity in the fmr1 Knockout Mouse.

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Brain Organoids and Therapeutic Development for Fragile X and Other Rare Diseases

Brain Organoids and Therapeutic Development for Fragile X and Other Rare Diseases

This is the first in a series of webinars focused on current topics in Fragile X research. In this webinar we hear from Alysson R. Muotri, PhD, Professor at University of California San Diego Stem Cell Programand Fabio C. Tucci, PhD, Chief Operating Officer and co-founder at Epigen Biosciences, Inc.

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Landmarks Light Up Fragile X Awareness Day 2020

Landmarks Light Up Fragile X Awareness Day 2020

This year, on Fragile X Awareness Day, a growing number of buildings, bridges, and monuments — including Niagara Falls — will be illuminated in teal to spread the word about Fragile X and celebrate our community. Although we may not be able to gather in groups this year, we still encourage you to briefly visit or drive by lighting displays and share your experience with us.

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FRAXA Biotech Games™ Reimagined as Online Event for 2020

FRAXA Biotech Games™ Reimagined as Online Event for 2020

FRAXA Biotech Games™, a gathering of Boston area biotech companies to network in a friendly setting, and form new relationships and potential collaborations while raising money for Fragile X research, is adapting its 2020 event to maintain its commitment to Fragile X and autism research while prioritizing the health and safety of its contestants and volunteers. The organization’s traditional annual event will be transformed into an online interactive experience September 9-11, 2020.

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