Kimberly Huber, PhD, explores hyperexcitability in Fragile X Syndrome

Kimberly Huber, PhD, explores hyperexcitability in Fragile X Syndrome

By Wei-Chung Allen Lee, Hayden Huang, Guoping Feng, Joshua R. Sanes, Emery N. Brown, Peter T. So, Elly Nedivi – Dynamic Remodeling of Dendritic Arbors in GABAergic Interneurons of Adult Visual Cortex. doi:10.1371/journal.pbio.0040029   Sensory Overload Ever wonder why your child with fragile X suddenly screams for no apparent reason or jumps and flaps uncontrollably seemingly for hours? You got it: hyperexcitability. But what exactly causes it? And what can fix it? Kimberly Huber, PhD, is working long and hard in her lab to answer those questions. Dr. Huber, professor, Neuroscience, UT Southwestern Medical Center, is seeking to understand how FMRP regulates connections between brain cells, called synapses, and the function of brain circuits, which are several connected brain cells. Her current focus is the study of synapses and brain circuits in the mouse that mediate sensory perception, including perception of touch and sound. She aims to understand the cellular and molecular

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