Fragile X Syndrome: In Pursuit of a Cure Webinar

Global webinar “Fragile X Syndrome: In Pursuit of a Cure” on July 22, 2021 commemorated World Fragile X Day. Over 5,000 registered from more than 50 countries.

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We Started Out Small, Now Look…

Join FRAXA in lighting up the world on July 22 for World Fragile X Day—together, we shine teal for Fragile X awareness!

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Dr. Bettio, Dr. Christie, Dr. Thacker

Targeting Adiponectin to Treat Fragile X Syndrome

Boosting adiponectin, a hormone that regulates metabolism, may improve cognition and behavior in Fragile X. Early results suggest it can restore brain plasticity.

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Ray Turner, PhD and Xiaoqin Zhan, PhD

Reintroducing FMRP via Tat to Reduce Symptoms of Fragile X Syndrome

A FRAXA-funded team found that a shortened FMRP protein, delivered with a Tat “carrier,” restores brain signaling and improves behavior in Fragile X mice.

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Metformin and Aberrant Insulin Signaling in a Fragile X Mouse Model

FRAXA-funded research is revealing how insulin signaling is altered in Fragile X and whether lowering it, including with metformin, could ease symptoms.

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18th International Fragile X and Related Neurodevelopmental Disorders Workshop, Quebec, Canada

Fragile X in the Forefront of International Conference

The 18th International Fragile X Workshop kicks off in Quebec, uniting global scientists to share breakthroughs in Fragile X and ASD.

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Encouraging Results from First Trial of Minocycline in Fragile X

A clinical trial of minocycline in children with Fragile X found significantly better global improvement vs. placebo, supporting its safety and potential.

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Iryna Ethell, PhD, at University of California

Researchers Propose Minocycline to Treat Fragile X

Researchers found that minocycline, an available drug that blocks MMP-9, may improve Fragile X symptoms. This discovery inspired clinical trials.

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FRAXA Funded Research

Current Research Grants (41)