Fragile X Research Foundation of Canada Archives • FRAXA Research Foundation

Fragile X Syndrome: In Pursuit of a Cure Webinar

July 29, 2021

Global webinar “Fragile X Syndrome: In Pursuit of a Cure” on July 22, 2021 commemorated World Fragile X Day. Over 5,000 registered from more than 50 countries.

We Started Out Small, Now Look…

May 13, 2021

Join FRAXA in lighting up the world on July 22 for World Fragile X Day—together, we shine teal for Fragile X awareness!

Targeting Adiponectin to Treat Fragile X Syndrome

October 29, 2019

FRAXA Research Foundation has awarded a $30,000 research grant to principal investigator Brian Christie, PhD, and postdoctoral fellows Jonathan Thacker, PhD, and Luis Bettio, PhD, at the University of Victoria. They are investigating whether boosting the hormone adiponectin can effectively treat Fragile X syndrome. This project is funded in partnership with the Fragile X Research Foundation of Canada, which is providing an additional $15,000.

Reintroducing FMRP via Tat to Reduce Symptoms of Fragile X Syndrome

March 26, 2019

FRAXA Research Foundation and the Fragile X Research Foundation of Canada awarded a grant of $100,000 over two years to Dr. Raymond Turner at the University of Calgary in Alberta, Canada. Dr. Turner and postdoctoral fellow Xiaoqin Zhan, PhD are attempting to reactivate a segment of FMRP to reverse symptoms of Fragile X in a mouse model of the disease to reduce abnormal behaviors.

Metformin and Aberrant Insulin Signaling in a Fragile X Mouse Model

November 2, 2018

This 2017-2018 grant of $90,000 is funded jointly by FRAXA and the Fragile X Research Foundation of Canada for the first year. A previous FRAXA grant to the Sonenberg lab has led to great interest in the available drug, metformin, as a potential treatment for Fragile X syndrome. FRAXA is currently organizing clinical trials of metformin.

18th International Fragile X and Related Neurodevelopmental Disorders Workshop, Quebec, Canada

Fragile X in the Forefront of International Conference

October 12, 2017

The 18th International Fragile X Workshop kicks off in Quebec, uniting global scientists to share breakthroughs in Fragile X and ASD.

Encouraging Results from First Trial of Minocycline in Fragile X

October 10, 2010

With a $40,000 grant from FRAXA, Dr. Carlo Paribello and his team at the Surrey Place Centre Fragile X clinic in Toronto, Ontario, ran an open label trial to see if minocycline can improve learning and reduce anxiety and behavioral problems in people with Fragile X. Twenty participants between the ages of 13 and 35 years took minocycline for two months.

Iryna Ethell, PhD, at University of California

Researchers Propose Minocycline to Treat Fragile X

October 4, 2008

This team has found that an available drug called minocycline, an inhibitor of mmp9, might also be used to treat Fragile X. Clinical trials later tested this.