Deep Molecular Profiling of Fragile X Mouse and Human Cells

Deep Molecular Profiling of Fragile X Mouse and Human Cells

FRAXA Research Foundation has awarded $90,000 to Dr. Joel Richter, Principal Investigator, and Dr. Sneha Shah, Postdoctoral Fellow, at the University of Massachusetts Medical School. They are using human induced pluripotent stem (iPS) cells to analyze gene expression in Fragile X syndrome.

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Fragile X Programs at UMASS – University of MA, Worcester

Fragile X Programs at UMASS – University of MA, Worcester
CANDO Team, left to right: Mary Beth Kadlec, Program Director, Occupational Therapist; David Cochran, Assistant Medical Director,Child Psychiatrist; Jean Frazier, Medical Director, Child Psychiatrist; Susan Swanson, Speech and Language Pathologist. (Not pictured: Van Silka, Adult Psychiatrist; Mary Crane, Board Certified Behavior Analyst;and Kelly Hurley, Autism Resource Specialist). Fragile X Programs aimed at improving the lives of individuals with Fragile X Syndrome at UMASS Medical School (UMMS) and UMASS Memorial Health Care (UMMHC) 1. Fragile X Syndrome Behavioral Health Clinic The Center for Autism and Neurodevelopmental Disorders (CANDO) is opening a specialty clinic for individuals with Fragile X Syndrome (under the direction of Dr. Jean Frazier) to evaluate and provide treatment for behavioral challenges. If you have questions about our program and/or have a need for our new clinical service, please call CANDO at 774-442-2263. 2. Expanded Fragile X Clinical Research The Child and Adolescent Neurodevelopment Initiative (CANDI, with Co-Directors Drs. Frazier and Kennedy) has two active studies aimed at expanding our knowledge about how toRead more

Correcting Fragile X Syndrome by Inhibiting the Synaptic RNA-Binding Protein CPEB1

Correcting Fragile X Syndrome by Inhibiting the Synaptic RNA-Binding Protein CPEB1

The Richter lab is the foremost research group in the world in the study of CPEB, a protein critical for regulation of protein synthesis. With $170,000 in grants from FRAXA Research Foundation over 2008-2011, Dr. Joel Richter of the University of MA Medical School explored whether inhibitions of the CPEB may be a viable approach for treatment of Fragile X.

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