Messenger RNA (mRNA) Archives • Page 4 of 4 • FRAXA Research Foundation

Holly Cline, PhD, at Cold Spring Harbor Laboratory, FRAXA research grant

FMRP Function in the Xenopus Visual System

February 27, 2004

With $75K from FRAXA, Dr. Holly Cline at Cold Spring Harbor studied Fragile X proteins and mRNA regulation in tadpoles.

Fruit Fly Helps Reveal the Secrets of Fragile X

February 26, 2004

FRAXA’s $50K grant supported Dr. Bassem Hassan’s Flanders team in using fruit flies to model Fragile X and guide future therapy studies.

Jerry Yin, PhD, at University of Wisconsin, FRAXA research grant

DFXR and Synaptic Tagging in Drosophila (Fruit Flies)

February 27, 2003

FRAXA’s $135K grant supported Dr. Jerry Yin’s Fragile X fruit fly studies on memory formation at Wisconsin’s Waisman Center.

Haruhiko Siomi, PhD, at Tokushima University, FRAXA research grant

Understanding the Function of Fragile X Protein in Drosophila

February 26, 2003

FRAXA-funded Tokushima researchers mapped the Drosophila FMR1 gene and its pathways, revealing how Fragile X disrupts cell function.

Isolating and Characterizing the mRNAs That Bind FMRP

January 14, 2003

With $60K from FRAXA, Dr. Denman’s team investigated how the Fragile X protein FMRP functions in the brain.

Structure of FMRP

February 27, 2002

With $68K from FRAXA, Dr. Lynne Regan at Yale studied how protein shapes influence Fragile X function. Results were published.

Robert Darnell, MD, PhD, at Rockefeller University, FRAXA research grant

Identification of Specific RNA Targets of FMRP

February 27, 2001

FRAXA-funded Dr. Darnell’s Rockefeller team uncovered how FMRP works and how its absence alters brain function. Published results.

Claudia Bagni, PhD, at University of Rome, FRAXA research grant

Molecular Interactions Between FMRP and Protein Translation Apparatus

February 27, 2001

FRAXA-funded Dr. Bagni uncovered how Fragile X disrupts protein synthesis control, advancing molecular understanding. Published results.

Justin Fallon, PhD, Brown University, FRAXA research grant

Transcriptional Regulation of the Fragile X Gene (fmr1) in the Olfactory Bulb

January 9, 2001

With $35K from FRAXA, Dr. Justin Fallon’s team at Brown University mapped Fragile X granules and explored FMRP’s role in sensorimotor function.

Transport of the Fragile X Protein

February 27, 2000

With $123K from FRAXA, Dr. Alan Tartakoff at Case Western studied how FMRP moves in the brain and advanced antibody tools for Fragile X research.

FMRP Function in the Xenopus Visual System

Fruit Fly Helps Reveal the Secrets of Fragile X

DFXR and Synaptic Tagging in Drosophila (Fruit Flies)

Understanding the Function of Fragile X Protein in Drosophila

Isolating and Characterizing the mRNAs That Bind FMRP

Structure of FMRP

Identification of Specific RNA Targets of FMRP

Molecular Interactions Between FMRP and Protein Translation Apparatus

Transcriptional Regulation of the Fragile X Gene (fmr1) in the Olfactory Bulb

Transport of the Fragile X Protein

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