STriatal-Enriched protein tyrosine Phosphatase (STEP) Archives • FRAXA Research Foundation

Memory Lane: New Research to Improve Memory in Fragile X Mice

June 27, 2016

University of Texas at Austin Researchers Daniel Johnston, PhD, and Jennifer J. Siegel, PhD, explore ways to Iimprove memory in Fragile X mice.

Can STEP Inhibitors Treat Fragile X Syndrome? Yale Professor Investigates

March 28, 2016

Yale Professor Paul Lombroso, MD, is testing STEP inhibitors to improve cognitive and social behaviors in those affected by Fragile X syndrome.

Claudia Bagni, PhD, at University of Rome, FRAXA research grant

Crossroads of Fragile X and Alzheimers Research

July 20, 2015

Last week researchers at VIB Leuven in Belgium published evidence that a brain pathway involving the protein APP (Amyloid Precursor Protein) plays a vital role in development of Fragile X syndrome, one of the most common causes of autism. Scientists led by Dr. Emanuela Pasciuto in the laboratory of Prof Claudia Bagni published findings of their study in the journal Neuron.

Paul Lombroso, PhD, Yale University, FRAXA Investigator

Inhibitors of STEP as a Novel Treatment of Fragile X Syndrome

February 26, 2015

STEP inhibition reversed behavioral and synaptic Fragile X deficits in mice (Neuropharmacology, 2018), highlighting STEP as a promising treatment target.

Memory Lane: New Research to Improve Memory in Fragile X Mice

Can STEP Inhibitors Treat Fragile X Syndrome? Yale Professor Investigates

Crossroads of Fragile X and Alzheimers Research

Inhibitors of STEP as a Novel Treatment of Fragile X Syndrome

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