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FRAXA Research Foundation – Finding a Cure for Fragile X Syndrome

FRAXA Research Foundation – Finding a Cure for Fragile X Syndrome

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STEP (STriatal-Enriched protein tyrosine Phosphatase)

Memory Lane: New Research to Improve Memory in Fragile X Mice

Theodore Coutilish June 27, 2016March 10, 2025
Dan Johnston and Jennifer Seigel

University of Texas at Austin Researchers Daniel Johnston, PhD, and Jennifer J. Siegel, PhD, explore ways to Iimprove memory in Fragile X mice.

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Can STEP Inhibitors Treat Fragile X Syndrome? Yale Professor Investigates

Theodore Coutilish March 28, 2016March 17, 2025

Yale Professor Paul Lombroso, MD, is testing STEP inhibitors to improve cognitive and social behaviors in those affected by Fragile X syndrome.

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Inhibitors of STEP as a Novel Treatment of Fragile X Syndrome

FRAXA Research Foundation February 26, 2015September 14, 2023
Paul Lombroso, PhD, Yale University, FRAXA Investigator

With a $349,000 grant from FRAXA Research Foundation from 2008-2015, Dr. Paul Lombroso and his team at Yale University researched if inhibiting STEP could reduce behavioral abnormalities in Fragile X syndrome. Results published.

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