organoid Archives

2021 Fragile X Research Grants Funded by FRAXA Research Foundation

FRAXA Research Foundation Research Updates October 1, 2021February 23, 2022astrocytes, autism, CBD, CRISPR, drug repurposing, EEG, endocannabinoid, FDA, lovastatin, metformin, microbiome, mRNAs, organoid

Each year, FRAXA funds a diverse portfolio of research. Our FRAXA Fellowships are seed funding for the future, the feedstock for the Fragile X treatment development pathway. While we are looking to promote as many promising new approaches as possible, prominent themes emerge each year, as scientists around the world tackle previously neglected areas.

Brain Organoids, Moving Fragile X Research Forward

Holly Roos Jin, Peng • Kang, Yunhee • Research Updates • Wen, Zhexing September 9, 2021November 22, 2021Alzheimer's, organoid

There are many ways research produces discoveries, and all of them include a process of steps that build on each other. When an exciting new avenue appeared with potential for Fragile X syndrome, FRAXA stepped up to fund it. We now see the results of this grant and are excited to share them with you. The importance of different types of models have been shared and discussed over many years. We are now adding a “brain organoid” model to this group, and the potential behind it is really exciting.

Towards Understanding the Role of FMRP in Human Brain Development Using Brain Organoids

FRAXA Research Foundation Jin, Peng • Seminar Series • Wen, Zhexing December 8, 2020December 8, 2020autism, cancer, DoD, epigenetics, FXPOI, FXTAS, mRNAs, NIH, organoid

Dr. Zhexing Wen and Dr. Peng Jin of the newly funded Fragile X Center of Excellence at Emory University School of Medicine join us in this seminar to present about Understanding the Role of FMRP in Human Brain Development Using Brain Organoids.

Brain Organoids and Therapeutic Development for Fragile X and Other Rare Diseases

FRAXA Research Foundation Research Updates • Seminar Series July 15, 2020May 11, 2022autism, drug repurposing, EEG, ERK, FDA, Healx, organoid, sound

This is the first in a series of webinars focused on current topics in Fragile X research. In this webinar we hear from Alysson R. Muotri, PhD, Professor at University of California San Diego Stem Cell Programand Fabio C. Tucci, PhD, Chief Operating Officer and co-founder at Epigen Biosciences, Inc.

Three-Dimensional Model for Identifying Fragile X Treatments

FRAXA Research Foundation 2018 Grants • 2019 Grants • Current Research Grants • Emory University • Jin, Peng • Kang, Yunhee • Resources • Treatment Targets • Wen, Zhexing May 16, 2018December 24, 2019neural stem cells, organoid

With a $90,000 grant from FRAXA Research Foundation awarded in 2018, Dr. Peng Jin and Dr. Juhnee Kang at Emory University will develop and analyze Fragile X brain organoids to understand the disorder and identify treatment targets.