Mega Green Tea Extract to Treat Fragile X?

Green tea is thought to have many benefits, particularly in cognitive function. In 2012-14, FRAXA Research Foundation funded a clinical trial to assess the effects of EGCG (green tea extract) on cognitive function in adults with FXS. Drs. Rafael de la Torre and Mara Dierssen Sotos, principal researchers in Barcelona, Spain, reported memory, attention, and mental flexibility improvements.

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Mara Dierssen, MD, PhD

Phase 1 Clinical Trial of Mega Green Tea Extract in Fragile X Syndrome

An early trial of green tea extract EGCG improved cognition in Fragile X. It targets ERβ and reduces overactive PI3K/mTOR/ERK signaling linked to FXS symptoms.

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FRAXA Funded Research

Current Research Grants (38)