Biomarker Discovery and Validation for Fragile X Syndrome

Biomarker Discovery and Validation for Fragile X Syndrome

With a $120,000 grant from FRAXA Research Foundation over 2015-2016, Dr. Eric Klann of New York University investigated potential new biomarkers in Fragile X syndrome and how to translate these markers from mouse models to human patients.

klann labRead more

The mTOR Pathway in Fragile X Syndrome

With a $90,000 grant from FRAXA Research Foundation over 2012-2013, Dr. Eric Klann and Postdoctoral Fellow Dr. Aditi Bhattacharrya of New York University investigated alterations in the mTOR pathway in Fragile X syndrome – which is also known to be defective in several forms of autism. Their work was published in September 2012 and received international attention.

FRAXA Research Foundation logoRead more

In Vivo Imaging of Synaptic Abnormalities in a Mouse Model of Fragile X Syndrome

In Vivo Imaging of Synaptic Abnormalities in a Mouse Model of Fragile X Syndrome

With an $85,000 grant from FRAXA Research Foundation over 2007-2008, Dr. Wen-Biao Gan and his team at New York University studied in-vivo protein development using imaging in mouse models to determine when pre- and postsynaptic structural plasticity occurs to target and when it develops abnormally.

Wen-Biao Gan, PhD, of New York University, FRAXA research grantRead more