Reactivation of the FMR1 Gene in Fragile X Patients Cells in Culture

FRAXA-funded Dr. Neri’s team in Italy tested strategies to reactivate the Fragile X gene, advancing curative research.

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Karel Svoboda, PhD, at Cold Spring Harbor Laboratory, FRAXA research grant

Imaging of Neocortical Dendritic Spine Maturation in FMR1 Knockout Mice Using Two-Photon Laser Scanning Microscopy

With $30K from FRAXA, Dr. Karel Svoboda’s team at Cold Spring Harbor studied dendritic spine changes in Fragile X mouse brain circuits.

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Psychophysiological Measures of Arousal: Documentation of Treatment Effects & Impact of Disability

With $60K from FRAXA, Dr. Don Bailey’s UNC team studied how arousal affects individuals with Fragile X, deepening understanding of behavior.

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W Ted Brown, MD, PhD

Improving Memory Reversal Testing and Treatment with AMPAkines in the Fragile X Knock-Out Mouse

FRAXA-funded Dr. W. Ted Brown studied learning deficits in Fragile X mice and tested Ampakine drugs for potential treatment.

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FRAXA Funded Research

Current Research Grants (38)