Paribello Carlo

Encouraging Results from First Trial of Minocycline in Fragile X

FRAXA Research Foundation 2006-2010 Grants • Clinical • Has Results • Paribello Carlo • Research Grant Results • Surrey Place Centre Toronto • Trials and Studies October 10, 2010April 27, 2020Fragile X Research Foundation of Canada, matrix metalloproteinase, mGluR5, minocycline, MMP9, Tetra Therapeutics

With a $40,000 grant from FRAXA, Dr. Carlo Paribello and his team at the Surrey Place Centre Fragile X clinic in Toronto, Ontario, ran an open label trial to see if minocycline can improve learning and reduce anxiety and behavioral problems in people with Fragile X. Twenty participants between the ages of 13 and 35 years took minocycline for two months.