Johnston, Daniel Archives

Prefrontal Cortex Network (PFC) Dynamics in Fragile X Syndrome

September 18, 2017

The team has shown that Fragile X mice have major prefrontal cortex deficits in Fragile X mice. Finding ways to overcome this could reveal new intervention strategies.

Prefrontal Cortex Network (PFC) Dynamics in Fragile X Syndrome

September 18, 2017

With a $90,000 grant from FRAXA Research Foundation from 2016-2017, Dr. Daniel Johnston and Dr. Jenni Siegel at the University of Texas at Austin are analyzing pre-frontal cortex (PFC) dysfunction in the Fragile X model. They have preliminary evidence that Fragile X mice are severely impaired in a prefrontal cortex (PFC)-dependent task.

Channelopathies: Altered Ion Channels in Fragile X Syndrome

September 15, 2014

Ion channel defects (“channelopathies”) in Fragile X disrupt neuron firing and network balance. This study maps these channel changes to guide targeted treatments.

Prefrontal Cortex Network (PFC) Dynamics in Fragile X Syndrome

Prefrontal Cortex Network (PFC) Dynamics in Fragile X Syndrome

Channelopathies: Altered Ion Channels in Fragile X Syndrome

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