Dan Johnston and Jennifer Seigel

Prefrontal Cortex Network (PFC) Dynamics in Fragile X Syndrome

The team has shown that Fragile X mice have major prefrontal cortex deficits in Fragile X mice. Finding ways to overcome this could reveal new intervention strategies.

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Channelopathies: Altered Ion Channels in Fragile X Syndrome

Ion channel defects (“channelopathies”) in Fragile X disrupt neuron firing and network balance. This study maps these channel changes to guide targeted treatments.

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FRAXA Funded Research

Current Research Grants (38)