Samie Jaffrey, PhD, at Weill Medical College of Cornell University, FRAXA research grant

Which is the right FMRP for Therapeutic Development of Fragile X Syndrome?

April 24, 2017

Many forms of FMRP exist in the brain. This project aims to pinpoint which versions of the protein are most critical to restore for effective Fragile X treatments.

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Molecular Mechanisms of Cytoskeletal Regulation by FMRP

January 9, 2015

With FRAXA funding, Dr. Jaffrey linked FMR1 loss to abnormal dendritic spines via RhoA signaling, suggesting RhoA-targeted therapies could help treat Fragile X.

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Samie Jaffrey, PhD, at Weill Medical College of Cornell University, FRAXA research grant

Scientists Uncover Trigger for Fragile X Syndrome

February 27, 2014

A Weill Cornell team discovered that Fragile X stems from a gene being shut off—and a compound that blocks this process may prevent the condition.

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FRAXA Funded Research

Current Research Grants (44)