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FRAXA Research Foundation – Finding a Cure for Fragile X Syndrome

FRAXA Research Foundation – Finding a Cure for Fragile X Syndrome

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FRAXA Funded Research

Research Type

Researcher

Research Organization

Grant Year

Gross, Christina

Christina Gross, PhD, Neuroscientist at Cincinnati’s Children’s Hospital Medical Center, researches the potential for shared underlying mechanisms in disorders like epilepsy and autism to develop stronger therapeutic treatments.

Gene Therapy Translational Studies for Fragile X Syndrome

FRAXA Research Foundation June 6, 2019January 29, 2024

With this $90,000 award from FRAXA Research Foundation, Drs. Ernest Pedapati, Christina Gross, and student Lindsay Beasley will pursue preclinical gene therapy approaches using AAV (adeno-associated virus) vectors for treating Fragile X syndrome at Cincinnati Children’s Hospital. Dr. Craig Erickson elaborates about this in this video.

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Genetic and Pharmacologic Manipulation of PI3K Activity in FXS: Assessing Potential Therapeutic Value

FRAXA Research Foundation September 2, 2012March 20, 2025

With a $90,000 grant from the FRAXA Research Foundation, Dr. Gary Bassell and his team at Emory University explored the PI3K/mTOR signaling complex in FXS via genetic and pharmacologic rescue approaches, to reduce the enzymatic function of specific components of this complex pathway in an FXS mouse model.

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