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FRAXA Research Foundation – Finding a Cure for Fragile X Syndrome

FRAXA Research Foundation – Finding a Cure for Fragile X Syndrome

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FRAXA Funded Research

Research Type

Researcher

Research Organization

Grant Year

Briault, Sylvain

Sylvain Briault, PhD, Team Leader at CNRS Orleans, researches neurodevelopmental disorders and received a FRAXA Research Foundation grant in 2012 to study certain drug effects on Fragile X mice.

BK Channel Openers: A New Hope for Fragile X Treatment – Insights from Kaerus Bioscience CEO Robert Ring

FRAXA Research Foundation October 22, 2024

Kaerus Bioscience’s BK channel openers for Fragile X syndrome are advancing through Phase 1 trials, offering hope for new treatments with FRAXA’s continued support.

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BK Channel Openers: A New Drug for Fragile X Is Ready for Clinical Trials

Michael Tranfaglia, MD May 31, 2024May 31, 2024

Discover the promising new BK channel opener, SPG601, now entering clinical trials for Fragile X syndrome. Learn about its potential to restore synaptic function and address core symptoms.

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Sensory Hypersensibility in Fragile X Syndrome and BK Channel Openers

FRAXA Research Foundation September 12, 2016February 28, 2025
FRAXA Research Team. From left to right: Sandrine Lefeuvre (PhD, Pharmacologist), Sylvain Briault (MD, PhD, head of the team), Julie Maublanc (PhD student, Pharmacologist), Olivier Perche (PhD, hospital engineer), Béatrice Laudier (MD, PhD student), Betty Hébert (PhD student), Arnaud Menuet (PhD, assistant professor) and Jacques Pichon (Professor, Dr es Science).

With $366,100 in grants from FRAXA Research Foundation, these investigators at the University of Orleans studied sensory abnormalities in Fragile X mice and test the ability of a class of drugs, BK channel openers, to rescue these abnormalities.

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