Brennan, Francis

Therapeutic Interventions in FMR1 Knockout and Transgenic Mice: Role of the FMR1 Gene

FRAXA Research Foundation 1994-2000 Grants • 2001-2005 Grants • 2006-2010 Grants • Albeck, David • Baylor College of Medicine • Brennan, Francis • Completed Research Grants • Disease Mechanisms • Paylor, Richard • Treatment Targets February 13, 2006April 25, 2018AMPA, AMPAkines, amyloid precursor protein, BDNF, PAK (p21-activated kinase), seizure, startle

With a $229,000 grant from FRAXA Research Foundation in 2006, Drs. Richard Paylor, David Albeck, and Francis Brennan at the Baylor College of Medicine found that, in mice as in humans, the level of Fragile X protein in brain cells plays a prominent role in determining levels of activity and anxiety.