15
SEP
2014

Join Survey Study for Families with Fragile X

    Attention Fragile X parents: here’s an easy survey study you can join. No travel needed because it’s online! The study’s goal is to help design...
10
SEP
2014
roche

Roche reports clinical trial negative results

Roche has shared the sad news that their clinical trials in Fragile X have been unsuccessful. They will host a Webcast on Thursday, September 18, from 12:30pm –...
04
SEP
2014
FRAXA 2013 spending on programs (Research and Education) was 93%, with just 7% spent on overhead (Fundraising and Management).

FRAXA Update Sept. 2014

New Clinical Trials Open for Participants We are delighted to see more Fragile X treatment trials underway! Before approving any new medication, the FDA requires two...
15
AUG
2014
Mike Tranfaglia, MD, FRAXA Chief Scientific Officer

Fragile X Clinical Trials: is the mGluR Theory still valid?

POSTED BY MICHAEL TRANFAGLIA MD Why have clinical trials failed?  Tolerance and Dose Range In my opinion, the Fragile X clinical trials of AFQ056 sponsored by Novartis failed...
06
AUG
2014

Fragile X Clinical Trials: Was Tolerance the Problem?

Further thoughts on our AFQ056 experience POSTED BY MICHAEL TRANFAGLIA MD The recent Fragile X clinical trials sponsored by Novartis ended with a rather negativ...
24
JUL
2014
Iryna Ethell

Fragile X Syndrome Treatment Target: MMP-9

A major article from the Ethell lab at UC Riverside has shown the therapeutic potential of drugs that inhibit the enzyme MMP-9. A nice lay description of the new pap...
26
JUN
2014
Dr. Mike Tranfaglia with son, Andy

Fragile X Clinical Trial: Novartis trial results are in, and they’re not pretty

AFQ056 Fragile X Clinical Trial showed Negative Results This year’s Gordon Conference just finished, and Novartis presented their results for the first time (though...
23
MAY
2014
USA Today logo

FRAXA Featured in USA Today: Disappointments aside, optimism for Fragile X drugs

On May 22, 2014, USA Today featured an article surrounding FRAXA’s optimism for continuing to seek effective treatments for Fragile X, despite negative results in...
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