Ruiting Zong, PhD, FRAXA Postdoctoral Fellow (2002)
Laura Kirkpatrick, PhD, FRAXA Postdoctoral Fellow (1998)
$60,000 in 2009
$70,000 in 2002
$40,000 in 2006
$60,000 in 1998
The Nelson lab has developed an impressive array of advanced mouse models of Fragile X. These models are available to other researchers thanks to funding from FRAXA and with additional support from The Meadows Foundation.
Fragile X Mutant Mouse Facility
by David Nelson, 6/10/2011
A Fragile X Mutant Mouse facility has been established at Baylor College of Medicine (BCM). A list of mouse strains is provided here.
FRAXA support has been essential for a broader and more rapid distribution of Fragile X and related gene mouse models. This has increased the pace of research into the role of FMR1 in a variety of areas. The BCM facility’s goal is to provide convenient and rapid access to new mouse models to investigators worldwide on request for modest costs of shipping.
This FRAXA sponsored Distribution Facility at Baylor College of Medicine has facilitated access to animals and tissues for Fragile X investigators worldwide. The AALAC certified Transgenic Mouse Facility at BCM is well suited to act as a repository for this activity. It has dedicated staff for animal shipment, and very well defined procedures for rapid and efficient transfer of mice. Moreover, the facility is (nearly) pathogen-free, allowing transfer of animals to most other academic mouse facilities with little or no delay due to quarantine.
During calendar years 2009 and 2010, 28 shipments were made to academic facilities in the United States, Canada, China and Chile. The facility remains popular in 2011. There has been demand for all mouse strains, although the Fmr1 mutations are most popular.
Mice are typically provided without restrictions (other than those required by the BCM standard Materials Transfer Agreement, which limits commercial use and re-distribution). In a small number of cases, where specific tissues and/or large numbers of animals have been requested, the Nelson group has engaged in a collaborative arrangement to acknowledge the extra time and effort required by Nelson lab personnel.
Please contact David Nelson directly at [email protected] to request mice or with any questions or concerns.