|Diagnosing the Methylation Status of the FMR1 Promoter Region in small numbers of Cells
Charles Laird, Ph.D., Principle Investigator (1996)
Reinhard Stoger, Ph.D, Postdoctoral Fellow (1996)
In Fragile X syndrome, the FMR1 gene does not produce its protein because the promoter region of the gene is methylated. " A potential therapeutic approach in treating individuals with this syndrome is reactivation of the endogenous gene by the use of demethylating pharmaceuticals".