|Fragile X Mutant Mouse Facility
by David Nelson, 6/10/2011
A Fragile X Mutant Mouse facility has been established at Baylor College of Medicine (BCM). A list of mouse strains is provided here.
FRAXA support has been essential for a broader and more rapid
distribution of Fragile X and related gene mouse models. This has
increased the pace of research into the role of FMR1 in a variety of areas.
The BCM facility’s goal is to provide convenient and rapid access to new
mouse models to investigators worldwide on request for modest costs of
This FRAXA sponsored Distribution Facility at Baylor College of Medicine
has facilitated access to animals and tissues for Fragile X investigators
worldwide. The AALAC certified Transgenic Mouse Facility at BCM is
well suited to act as a repository for this activity. It has dedicated staff for
animal shipment, and very well defined procedures for rapid and efficient
transfer of mice. Moreover, the facility is (nearly) pathogen-free, allowing
transfer of animals to most other academic mouse facilities with little or no
delay due to quarantine.
During calendar years 2009 and 2010, 28 shipments were made to
academic facilities in the United States, Canada, China and Chile. The
facility remains popular in 2011. There has been demand for all mouse
strains, although the Fmr1 mutations are most popular.
Mice are typically provided without restrictions (other than those required
by the BCM standard Materials Transfer Agreement, which limits
commercial use and re-distribution). In a small number of cases, where
specific tissues and/or large numbers of animals have been requested, the
Nelson group has engaged in a collaborative arrangement to acknowledge
the extra time and effort required by Nelson lab personnel.
Please contact David Nelson directly at firstname.lastname@example.org to request mice or with any questions or concerns.