|Final Report on Dr. Dyken's Project
by Katie Clapp, FRAXA, 1/1/2004
This team found that young males with Fragile X have profound deficits in prepulse inhibition (PPI), a basic marker of sensorimotor gating that has been extensively studied in rodents. Importantly, the magnitude of the PPI impairments in the Fragile X children predicted the severity of their IQ, attention, adaptive behavior and autistic phenotypes.
Complete results were published in 2004.