|The role of GABAergic inhibitory function in Fragile X Syndrome
Joshua Corbin, MD, PhD, Principal Investigator
Molly Huntsman, PhD, Co-Investigator
$50,000 in 2010
$50,000 in 2009
This team is examining the role of particular class of brain cells (inhibitory interneurons) that dampen excessive activity in the “emotional center of the brain” (the amydala). This inhibition is deficient in Fragile X, and so they are looking for ways to remedy this.This is particularly interesting to parents of children who are overly anxious and emotional. They are working with Dr. Walter Kaufmann, a clinician at Kennedy Krieger Institute in Maryland.