FRAXA funds research teams around the world! Purple are 2012 funded. Scroll below to view teams by chief scientist. View FRAXA Research Teams in a larger map
FRAXA Research Teams by Principal Investigator
Funded 2012
network activity
mRNAs
reactivating FMR1
Treatment Target
Therapeutic treatments
Validation of drugs
Clinical Trial
biomarkers
Clinical Trial
Therapeutic options
FMRP and BDNF-TrkB
mGluR5 Theory
Therapies
autism, FX
signaling pathways
Synaptic transmission
endocannabinoids
Minocycline
synaptic pathways
APP
Social behavior
Role of GLT1
Funded 2011
endocannabinoids
mGluRs
clinical trials
Reward in FXS
treatment trial
ion channels
GSK3
dendritic proteins
mouse models
mGluRs
CPEB
drug screen
Rac and Rho
cAMP
JNK
plasticity
signaling pathways
Funded 2010
GABA/amygdala
channelopathies
lithium enhancers
clinical trials
drug screen
GABA
STEP
gene reactivation
clinical trials
small RNAs
disease mechanisms
Funded 2009
fly FMRP function
minocycline
synaptic plasticity
APP
preclin.pharmacology
disease mechanisms
mGluRs
mRNAs
GABA, epigenetics
Funded 2008
fly sleep
Amygdala in FXS
AMPA receptors
RNA splicing
synapse turnover
development
synaptic plasticity
mGluRs
metabolism
minocycline
zebrafish
proteomics
Funded 2007
treatment
endocrine function
mGluR Trafficking
MAP1B
Funded 2006
mice
FMRP in bird song
mouse behavior
neocortex
treatment trial
fly motor function
fruit fly CYFIP
inhibitory circuits
presynaptic FMRP
Prader-Willi, FX
autism, FX
mouse behavior
mouse behavior
isoforms of FMRP
mouse behavior
protein synthesis
epilepsy
proteins
Funded 2005
FMRP targets
presynaptic FMRP
Target mRNAs
HPA Axis
brain circuits
FMRP and PAK
microRNAs
Funded 2004
RNA
tadpoles
fruit flies
gene repair
frog model
stem cells
Funded 2003
fly dendrites
mouse behavior
GABA receptors
gene studies
FMRP binding
fruit flies
Funded 2002
gene therapy
mouse model
fruit flies
gene therapy
RNAs that bind
Funded 2001
proteins
Target mRNAs
behavior
FMRP regulation
receptors
Funded 2000
child behavior
learning
memory
Protein interactions
synapses
FMRP function
Funded 1999
FMR1 Gene
clinical trial
mouse/human PPI
Funded 1998
Fragile X Knock-Out Mouse
Funded 1996
FMR1 Promoter